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You test whether a new staining protocol detects a specific cell type in tissue sections. On your first try, you see no staining in your experimental samples. Which added control would MOST directly tell you whether the staining protocol itself can work (i.e., whether “no staining” might be a technical failure)?

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Course
Introductory Biology Foundations: Cells, Genes, Evolution & Ecol
10 units46 lessons
Topics
Biology (introductory)Biochemistry (intro level)Cell & Molecular BiologyGeneticsEvolutionary BiologyEcology
About this course

Build a strong, integrated introduction to biology by learning core vocabulary and the cause–effect logic that connects biochemistry, cells, genes, evolution, and ecosystems. Focus on how science generates and tests explanations through hypotheses, experimental design (controls, independent/dependent variables), and evidence-based interpretation. Develop quantitative comfort with simple graphs, proportions, and frequency reasoning (including Hardy–Weinberg). Master key structure–function themes (macromolecules, enzymes, membranes, organelles), information flow (DNA→RNA→protein, mutations), energy transformations (ATP, respiration), inheritance (meiosis, Mendelian patterns), evolutionary mechanisms, and ecological energy flow and interactions.